My gut feeling is that eventually this will also hook into research into ME / CFS and hopefully shed light on the awful psychological / neurological symptoms that assail ME-sufferers.
"Comparing blood, DNA and tissue samples from the stressed small mice, nine control mice and mice that were more relaxed in the presence of big bruisers suggests that there are three stages in the process of social stress leading to an altered mood. First, the stress kicks off inflammation in the bloodstream. This then weakens the blood-brain barrier, which normally protects the brain, making it leaky and more likely to let substances through into the brain.
"This enables large molecules like inflammatory substance interleukin-6 and aggressive white blood cells called monocytes to pass into the brain. Here they seem to disrupt signalling in the nucleus accumbens, a part of the brain that helps evaluate threats and rewards."