Most MRSA is brought onto wards by vistors - usually the ones that don't like alcohol hand-rubs ("It dries my skin up!") - weirdly, they're often the ones who are quickest to litigate when poor old Grandma or 87-year old Uncle Fred gets a post-surgical infection that they probably passed onto them... but hey-ho, you really don't want to get me started about people who needlessly litigate against the NHS, who are - you know - basically sueing you and I.
Anything that makes MRSA and other wide-spectrum-resistant bugs less of a life-claimer / resource-swallower is of interest to me on a bunch of levels.
"In this new study, the authors used whole genome sequences from 90 MRSA isolates to identify over 100 genetic loci associated with toxicity. Despite belonging to the same ST239 clone, the isolates varied greatly in toxicity.
"Importantly, the highly toxic isolates shared a common genetic signature. By looking for this signature in the MRSA genome, the researchers were able to predict which isolates were the most toxic and thus more likely to cause severe disease..."